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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1990 2
1991 7
1992 7
1993 25
1994 25
1995 48
1996 40
1997 56
1998 61
1999 47
2000 37
2001 38
2002 38
2003 50
2004 56
2005 46
2006 39
2007 45
2008 52
2009 63
2010 49
2011 91
2012 116
2013 108
2014 146
2015 144
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2023 32
2024 6

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1,953 results

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Page 1
CD44: A Multifunctional Mediator of Cancer Progression.
Hassn Mesrati M, Syafruddin SE, Mohtar MA, Syahir A. Hassn Mesrati M, et al. Biomolecules. 2021 Dec 9;11(12):1850. doi: 10.3390/biom11121850. Biomolecules. 2021. PMID: 34944493 Free PMC article. Review.
Nonetheless, high CD44 expression significantly contributes to enhanced tumourigenic mechanisms, such as cell proliferation, metastasis, invasion, migration and stemness; hence, CD44 is an important clinical target. ...The clinical significance and prognostic …
Nonetheless, high CD44 expression significantly contributes to enhanced tumourigenic mechanisms, such as cell proliferation, metas …
Role of CD44 isoforms in epithelial-mesenchymal plasticity and metastasis.
Primeaux M, Gowrikumar S, Dhawan P. Primeaux M, et al. Clin Exp Metastasis. 2022 Jun;39(3):391-406. doi: 10.1007/s10585-022-10146-x. Epub 2022 Jan 12. Clin Exp Metastasis. 2022. PMID: 35023031 Free PMC article. Review.
CD44 expression is complex, with alternative splicing producing many isoforms. Interestingly, not only does the pattern of isoform expression change during transitions between epithelial and mesenchymal phenotypes in cancer, but these isoforms have distinct effects on cell …
CD44 expression is complex, with alternative splicing producing many isoforms. Interestingly, not only does the pattern of isoform ex …
Targeting metastasis-initiating cells through the fatty acid receptor CD36.
Pascual G, Avgustinova A, Mejetta S, Martín M, Castellanos A, Attolini CS, Berenguer A, Prats N, Toll A, Hueto JA, Bescós C, Di Croce L, Benitah SA. Pascual G, et al. Nature. 2017 Jan 5;541(7635):41-45. doi: 10.1038/nature20791. Epub 2016 Dec 7. Nature. 2017. PMID: 27974793
Here we describe a subpopulation of CD44(bright) cells in human oral carcinomas that do not overexpress mesenchymal genes, are slow-cycling, express high levels of the fatty acid receptor CD36 and lipid metabolism genes, and are unique in their ability to initiate metas …
Here we describe a subpopulation of CD44(bright) cells in human oral carcinomas that do not overexpress mesenchymal genes, are slow-c …
CD44 and Tumor-Derived Extracellular Vesicles (TEVs). Possible Gateway to Cancer Metastasis.
Szatanek R, Baj-Krzyworzeka M. Szatanek R, et al. Int J Mol Sci. 2021 Feb 2;22(3):1463. doi: 10.3390/ijms22031463. Int J Mol Sci. 2021. PMID: 33540535 Free PMC article. Review.
Cancer metastasis, the final stage of tumor progression, is a complex process governed by the interplay of multiple types of cells and the tumor microenvironment. ...This review covers the present information regarding the TEVs-mediated CD44s/CD44v transfer/interaction in …
Cancer metastasis, the final stage of tumor progression, is a complex process governed by the interplay of multiple types of cells an …
CD44 and its partners in metastasis.
Jothy S. Jothy S. Clin Exp Metastasis. 2003;20(3):195-201. doi: 10.1023/a:1022931016285. Clin Exp Metastasis. 2003. PMID: 12741678 Review.
The establishment of metastasis requires that tumor cells acquire new adhesion and migration properties to emigrate from primary sites and colonize distant organs. ...This review summarizes current knowledge on the role of CD44 in metastasis, as well as the c …
The establishment of metastasis requires that tumor cells acquire new adhesion and migration properties to emigrate from primary site …
CD44 and HCELL: preventing hematogenous metastasis at step 1.
Jacobs PP, Sackstein R. Jacobs PP, et al. FEBS Lett. 2011 Oct 20;585(20):3148-58. doi: 10.1016/j.febslet.2011.07.039. Epub 2011 Aug 5. FEBS Lett. 2011. PMID: 21827751 Free PMC article. Review.
Despite great strides in our knowledge of the genetic and epigenetic changes underlying malignancy, we have limited information on the molecular basis of metastasis. Over 90% of cancer deaths are caused by spread of tumor cells from a primary site to distant organs and tis …
Despite great strides in our knowledge of the genetic and epigenetic changes underlying malignancy, we have limited information on the molec …
CD44 in inflammation and metastasis.
Lesley J, Hyman R, English N, Catterall JB, Turner GA. Lesley J, et al. Glycoconj J. 1997 Aug;14(5):611-22. doi: 10.1023/a:1018540610858. Glycoconj J. 1997. PMID: 9298694 Review.
CD44 is a major cell surface receptor for the glycosaminoglycan, hyaluronan (HA). ...CD44 binding of HA is regulated by the cells in which it is expressed. ...
CD44 is a major cell surface receptor for the glycosaminoglycan, hyaluronan (HA). ...CD44 binding of HA is regulated by …
HAS2 and CD44 in breast tumorigenesis.
Heldin P, Basu K, Kozlova I, Porsch H. Heldin P, et al. Adv Cancer Res. 2014;123:211-29. doi: 10.1016/B978-0-12-800092-2.00008-3. Adv Cancer Res. 2014. PMID: 25081531 Review.
Metastatic spread of breast cancer cells, facilitated by the epithelial-mesenchymal transition (EMT) process, is responsible for the majority of breast cancer mortality. Increased levels of hyaluronan due to deregulation of hyaluronan-synthesizing enzymes, like HAS2 …
Metastatic spread of breast cancer cells, facilitated by the epithelial-mesenchymal transition (EMT) process, is responsible for the majorit …
CD44 in Bone Metastasis Development: A Key Player in the Fate Decisions of the Invading Cells?
Zer NS, Ben-Ghedalia-Peled N, Gheber LA, Vago R. Zer NS, et al. Clin Exp Metastasis. 2023 Apr;40(2):125-135. doi: 10.1007/s10585-023-10203-z. Epub 2023 Apr 10. Clin Exp Metastasis. 2023. PMID: 37038009 Review.
A participant in key developmental processes, the adhesion glycoprotein CD44 is also expressed in several types of malignancies and can promote metastasis. ...In this review, we summarize the current data on the roles played by CD44 in cancer progression and …
A participant in key developmental processes, the adhesion glycoprotein CD44 is also expressed in several types of malignancies and c …
CD44 overexpression related to lymph node metastasis and poor prognosis of pancreatic cancer.
Liu Y, Wu T, Lu D, Zhen J, Zhang L. Liu Y, et al. Int J Biol Markers. 2018 Aug;33(3):308-313. doi: 10.1177/1724600817746951. Epub 2018 Apr 23. Int J Biol Markers. 2018. PMID: 29683068 Free article.
BACKGROUND: CD44 has recently been reported as a biomarker for pancreatic cancer. ...T1,2); 95% CI 1.28, 4.52; P = 0.007), and more advanced TNM stage (OR 4.53 (III~IV vs. I~II); 95% CI 1.46, 14.08; P = 0.01). However, CD44 overexpression was not associated with oth …
BACKGROUND: CD44 has recently been reported as a biomarker for pancreatic cancer. ...T1,2); 95% CI 1.28, 4.52; P = 0.007), and more a …
1,953 results